diff --git a/packages/insomnia-smoke-test/fixtures/pre-request-collection.yaml b/packages/insomnia-smoke-test/fixtures/pre-request-collection.yaml
index af541d9d0e..f7e561d3b5 100644
--- a/packages/insomnia-smoke-test/fixtures/pre-request-collection.yaml
+++ b/packages/insomnia-smoke-test/fixtures/pre-request-collection.yaml
@@ -1047,3 +1047,33 @@ resources:
           "asyncTaskDone": {{ _.asyncTaskDone}}
         }
     _type: request
+  - _id: req_89dade2ee9ee42fbb22d588783a9df15
+    parentId: fld_01de564274824ecaad272330339ea6b2
+    modified: 1636707449231
+    created: 1636141014552
+    url: http://127.0.0.1:4010/echo
+    name: persist environment
+    description: ""
+    method: POST
+    parameters: []
+    headers:
+      - name: 'Content-Type'
+        value: 'application/json'
+    authentication: {}
+    metaSortKey: -1636141014553
+    isPrivate: false
+    settingStoreCookies: true
+    settingSendCookies: true
+    settingDisableRenderRequestBody: false
+    settingEncodeUrl: true
+    settingRebuildPath: true
+    settingFollowRedirects: global
+    preRequestScript: |-
+      insomnia.environment.set('__fromScript', 'environment');
+      insomnia.baseEnvironment.set('__fromScript1', 'baseEnvironment');
+      insomnia.collectionVariables.set('__fromScript2', 'collection');
+    body:
+      mimeType: "application/json"
+      text: |-
+        {}
+    _type: request
diff --git a/packages/insomnia-smoke-test/tests/smoke/pre-request-script-features.test.ts b/packages/insomnia-smoke-test/tests/smoke/pre-request-script-features.test.ts
index 2f2abc877d..4fecffecfd 100644
--- a/packages/insomnia-smoke-test/tests/smoke/pre-request-script-features.test.ts
+++ b/packages/insomnia-smoke-test/tests/smoke/pre-request-script-features.test.ts
@@ -408,6 +408,30 @@ test.describe('pre-request features tests', async () => {
         await expect(responsePane).toContainText('✓ happy tests'); // original proxy
         await expect(responsePane).toContainText('✕ unhappy tests: AssertionError: expected 199 to deeply equal 200'); // updated proxy
     });
+
+    test('environment and baseEnvironment can be persisted', async ({ page }) => {
+        const statusTag = page.locator('[data-testid="response-status-tag"]:visible');
+        await page.getByLabel('Request Collection').getByTestId('persist environment').press('Enter');
+
+        // send
+        await page.getByTestId('request-pane').getByRole('button', { name: 'Send' }).click();
+
+        // verify response
+        await page.waitForSelector('[data-testid="response-status-tag"]:visible');
+        await expect(statusTag).toContainText('200 OK');
+
+        // verify persisted environment
+        await page.getByLabel('Manage Environments').click();
+        const responseBody = page.getByRole('dialog').getByTestId('CodeEditor').locator('.CodeMirror-line');
+        const rows = await responseBody.allInnerTexts();
+        const bodyJson = JSON.parse(rows.join(' '));
+
+        expect(bodyJson).toEqual({
+            // no environment is selected so the environment value is not persisted
+            '__fromScript1': 'baseEnvironment',
+            '__fromScript2': 'collection',
+        });
+    });
 });
 
 test.describe('unhappy paths', async () => {
diff --git a/packages/insomnia/src/ui/routes/request.tsx b/packages/insomnia/src/ui/routes/request.tsx
index dde7fa05e9..c3305d7305 100644
--- a/packages/insomnia/src/ui/routes/request.tsx
+++ b/packages/insomnia/src/ui/routes/request.tsx
@@ -401,6 +401,27 @@ export const sendAction: ActionFunction = async ({ request, params }) => {
           { cookies: mutatedContext.cookieJar.cookies },
         );
       }
+      // when base environment is activated, `mutatedContext.environment` points to it
+      const isActiveEnvironmentBase = mutatedContext.environment?._id === baseEnvironment._id;
+      const hasEnvironmentAndIsNotBase = mutatedContext.environment && !isActiveEnvironmentBase;
+      if (hasEnvironmentAndIsNotBase) {
+        await models.environment.update(
+          environment,
+          {
+            data: mutatedContext.environment.data,
+            dataPropertyOrder: mutatedContext.environment.dataPropertyOrder,
+          }
+        );
+      }
+      if (mutatedContext.baseEnvironment) {
+        await models.environment.update(
+          baseEnvironment,
+          {
+            data: mutatedContext.baseEnvironment.data,
+            dataPropertyOrder: mutatedContext.baseEnvironment.dataPropertyOrder,
+          }
+        );
+      }
     }
 
     const renderedResult = await tryToInterpolateRequest(