diff --git a/.changeset/clean-worms-fetch.md b/.changeset/clean-worms-fetch.md
new file mode 100644
index 0000000000..511f770867
--- /dev/null
+++ b/.changeset/clean-worms-fetch.md
@@ -0,0 +1,5 @@
+---
+"@pnpm/resolve-dependencies": patch
+---
+
+The lockfile needs to be updated when the value of neverBuiltDependencies changes.
diff --git a/packages/resolve-dependencies/src/updateLockfile.ts b/packages/resolve-dependencies/src/updateLockfile.ts
index da3d3ae244..493301f844 100644
--- a/packages/resolve-dependencies/src/updateLockfile.ts
+++ b/packages/resolve-dependencies/src/updateLockfile.ts
@@ -146,7 +146,11 @@ function toLockfileDependency (
   if (pkg.hasBin) {
     result['hasBin'] = true
   }
-  if (opts.prevSnapshot) {
+  if (pkg.requiresBuild !== undefined) {
+    if (pkg.requiresBuild) {
+      result['requiresBuild'] = true
+    }
+  } else if (opts.prevSnapshot) {
     if (opts.prevSnapshot.requiresBuild) {
       result['requiresBuild'] = opts.prevSnapshot.requiresBuild
     }
@@ -156,10 +160,6 @@ function toLockfileDependency (
   } else if (pkg.prepare) {
     result['prepare'] = true
     result['requiresBuild'] = true
-  } else if (pkg.requiresBuild !== undefined) {
-    if (pkg.requiresBuild) {
-      result['requiresBuild'] = true
-    }
   } else {
     pendingRequiresBuilds.push(opts.depPath)
   }
diff --git a/packages/supi/test/install/lifecycleScripts.ts b/packages/supi/test/install/lifecycleScripts.ts
index fd34c973b1..f2724cffa1 100644
--- a/packages/supi/test/install/lifecycleScripts.ts
+++ b/packages/supi/test/install/lifecycleScripts.ts
@@ -458,3 +458,36 @@ test('selectively ignore scripts in some dependencies', async () => {
   expect(await exists('node_modules/pre-and-postinstall-scripts-example/generated-by-postinstall.js')).toBeFalsy()
   expect(await exists('node_modules/install-script-example/generated-by-install.js')).toBeTruthy()
 })
+
+test('lockfile is updated if neverBuiltDependencies is changed', async () => {
+  const project = prepareEmpty()
+  const manifest = await addDependenciesToPackage({},
+    ['pre-and-postinstall-scripts-example', 'install-script-example'],
+    await testDefaults({ fastUnpack: false })
+  )
+
+  {
+    const lockfile = await project.readLockfile()
+    expect(lockfile.neverBuiltDependencies).toBeFalsy()
+    expect(lockfile.packages['/pre-and-postinstall-scripts-example/1.0.0'].requiresBuild).toBeTruthy()
+    expect(lockfile.packages['/install-script-example/1.0.0'].requiresBuild).toBeTruthy()
+  }
+
+  const neverBuiltDependencies = ['pre-and-postinstall-scripts-example']
+  manifest.pnpm = { neverBuiltDependencies }
+  await mutateModules([
+    {
+      buildIndex: 0,
+      manifest,
+      mutation: 'install',
+      rootDir: process.cwd(),
+    },
+  ], await testDefaults())
+
+  {
+    const lockfile = await project.readLockfile()
+    expect(lockfile.neverBuiltDependencies).toStrictEqual(neverBuiltDependencies)
+    expect(lockfile.packages['/pre-and-postinstall-scripts-example/1.0.0'].requiresBuild).toBe(undefined)
+    expect(lockfile.packages['/install-script-example/1.0.0'].requiresBuild).toBeTruthy()
+  }
+})