diff --git a/.changeset/silver-lions-repair.md b/.changeset/silver-lions-repair.md
new file mode 100644
index 0000000000..c82d238a98
--- /dev/null
+++ b/.changeset/silver-lions-repair.md
@@ -0,0 +1,5 @@
+---
+"@pnpm/global-bin-dir": patch
+---
+
+`npx pnpm install --global pnpm` should not install pnpm to the temporary directory of npx.
diff --git a/packages/global-bin-dir/src/index.ts b/packages/global-bin-dir/src/index.ts
index 956aaf0327..51c2cc4497 100644
--- a/packages/global-bin-dir/src/index.ts
+++ b/packages/global-bin-dir/src/index.ts
@@ -31,14 +31,14 @@ function pickBestGlobalBinDir (
   const noWriteAccessDirs = [] as string[]
   for (const dir of dirs) {
     const lowCaseDir = dir.toLowerCase()
-    if (
+    if ((
       isUnderDir('node', lowCaseDir) ||
       isUnderDir('nodejs', lowCaseDir) ||
       isUnderDir('npm', lowCaseDir) ||
       isUnderDir('pnpm', lowCaseDir) ||
       knownCandidates.some((candidate) => areDirsEqual(candidate, dir)) ||
       dirHasNodeRelatedCommand(dir)
-    ) {
+    ) && !isUnderDir('_npx', lowCaseDir)) {
       if (canWriteToDirAndExists(dir)) return dir
       noWriteAccessDirs.push(dir)
     }
diff --git a/packages/global-bin-dir/test/index.ts b/packages/global-bin-dir/test/index.ts
index f34bf2955b..f2728cecf1 100644
--- a/packages/global-bin-dir/test/index.ts
+++ b/packages/global-bin-dir/test/index.ts
@@ -41,10 +41,12 @@ const userGlobalBin = makePath('usr', 'local', 'bin')
 const nodeGlobalBin = makePath('home', 'z', '.nvs', 'node', '12.0.0', 'x64', 'bin')
 const npmGlobalBin = makePath('home', 'z', '.npm')
 const pnpmGlobalBin = makePath('home', 'z', '.pnpm')
+const npxGlobalBin = makePath('home', 'z', '.npm', '_npx', '123')
 const otherDir = makePath('some', 'dir')
 const currentExecDir = makePath('current', 'exec')
 const dirWithTrailingSlash = `${makePath('current', 'slash')}${path.sep}`
 process.env[FAKE_PATH] = [
+  npxGlobalBin,
   userGlobalBin,
   nodeGlobalBin,
   npmGlobalBin,