diff --git a/.changeset/huge-apples-hang.md b/.changeset/huge-apples-hang.md
new file mode 100644
index 0000000000..6d2d06db7d
--- /dev/null
+++ b/.changeset/huge-apples-hang.md
@@ -0,0 +1,5 @@
+---
+"@pnpm/plugin-commands-script-runners": patch
+---
+
+When executing the `pnpm create` command, must verify whether the node version is supported even if a cache already exists.
diff --git a/exec/plugin-commands-script-runners/package.json b/exec/plugin-commands-script-runners/package.json
index 8a53e8027c..3048acbcb8 100644
--- a/exec/plugin-commands-script-runners/package.json
+++ b/exec/plugin-commands-script-runners/package.json
@@ -73,6 +73,7 @@
     "@pnpm/logger": "catalog:"
   },
   "devDependencies": {
+    "@pnpm/env.system-node-version": "workspace:*",
     "@pnpm/filter-workspace-packages": "workspace:*",
     "@pnpm/logger": "workspace:*",
     "@pnpm/plugin-commands-script-runners": "workspace:*",
diff --git a/exec/plugin-commands-script-runners/src/dlx.ts b/exec/plugin-commands-script-runners/src/dlx.ts
index faa12e8b13..6b154cade1 100644
--- a/exec/plugin-commands-script-runners/src/dlx.ts
+++ b/exec/plugin-commands-script-runners/src/dlx.ts
@@ -1,7 +1,7 @@
 import fs, { type Stats } from 'fs'
 import path from 'path'
 import util from 'util'
-import { docsUrl } from '@pnpm/cli-utils'
+import { docsUrl, readProjectManifestOnly } from '@pnpm/cli-utils'
 import { createResolver } from '@pnpm/client'
 import { parseWantedDependency } from '@pnpm/parse-wanted-dependency'
 import { OUTPUT_OPTIONS } from '@pnpm/common-cli-options-help'
@@ -11,7 +11,7 @@ import { PnpmError } from '@pnpm/error'
 import { add } from '@pnpm/plugin-commands-installation'
 import { readPackageJsonFromDir } from '@pnpm/read-package-json'
 import { getBinsFromPackageManifest } from '@pnpm/package-bins'
-import { type PnpmSettings, type SupportedArchitectures } from '@pnpm/types'
+import { type PackageManifest, type PnpmSettings, type SupportedArchitectures } from '@pnpm/types'
 import { lexCompare } from '@pnpm/util.lex-comparator'
 import execa from 'execa'
 import pick from 'ramda/src/pick'
@@ -138,15 +138,14 @@ export async function handler (
       }
     }
   }
-  const modulesDir = path.join(cachedDir, 'node_modules')
-  const binsDir = path.join(modulesDir, '.bin')
+  const binsDir = path.join(cachedDir, 'node_modules/.bin')
   const env = makeEnv({
     userAgent: opts.userAgent,
     prependPaths: [binsDir, ...opts.extraBinPaths],
   })
   const binName = opts.package
     ? command
-    : await getBinName(modulesDir, await getPkgName(cachedDir))
+    : await getBinName(cachedDir, opts)
   try {
     await execa(binName, args, {
       cwd: process.cwd(),
@@ -174,9 +173,10 @@ async function getPkgName (pkgDir: string): Promise<string> {
   return dependencyNames[0]
 }
 
-async function getBinName (modulesDir: string, pkgName: string): Promise<string> {
-  const pkgDir = path.join(modulesDir, pkgName)
-  const manifest = await readPackageJsonFromDir(pkgDir)
+async function getBinName (cachedDir: string, opts: Pick<DlxCommandOptions, 'engineStrict'>): Promise<string> {
+  const pkgName = await getPkgName(cachedDir)
+  const pkgDir = path.join(cachedDir, 'node_modules', pkgName)
+  const manifest = await readProjectManifestOnly(pkgDir, opts) as PackageManifest
   const bins = await getBinsFromPackageManifest(manifest, pkgDir)
   if (bins.length === 0) {
     throw new PnpmError('DLX_NO_BIN', `No binaries found in ${pkgName}`)
diff --git a/exec/plugin-commands-script-runners/test/dlx.e2e.ts b/exec/plugin-commands-script-runners/test/dlx.e2e.ts
index ad2538d624..6885bb509d 100644
--- a/exec/plugin-commands-script-runners/test/dlx.e2e.ts
+++ b/exec/plugin-commands-script-runners/test/dlx.e2e.ts
@@ -2,6 +2,7 @@ import fs from 'fs'
 import path from 'path'
 import { add } from '@pnpm/plugin-commands-installation'
 import { dlx } from '@pnpm/plugin-commands-script-runners'
+import * as systemNodeVersion from '@pnpm/env.system-node-version'
 import { prepareEmpty } from '@pnpm/prepare'
 import { DLX_DEFAULT_OPTS as DEFAULT_OPTS } from './utils'
 
@@ -235,6 +236,20 @@ test('dlx with cache', async () => {
   expect(spy).not.toHaveBeenCalled()
 
   spy.mockRestore()
+
+  // Specify a node version that shx@0.3.4 does not support. Currently supported versions are >= 6.
+  const spySystemNodeVersion = jest.spyOn(systemNodeVersion, 'getSystemNodeVersion').mockReturnValue('v4.0.0')
+
+  await expect(dlx.handler({
+    ...DEFAULT_OPTS,
+    engineStrict: true,
+    dir: path.resolve('project'),
+    storeDir: path.resolve('store'),
+    cacheDir: path.resolve('cache'),
+    dlxCacheMaxAge: Infinity,
+  }, ['shx@0.3.4', 'touch', 'foo'])).rejects.toThrow('Unsupported engine for')
+
+  spySystemNodeVersion.mockRestore()
 })
 
 test('dlx does not reuse expired cache', async () => {
diff --git a/exec/plugin-commands-script-runners/tsconfig.json b/exec/plugin-commands-script-runners/tsconfig.json
index 5907592ad1..3a0fc56cac 100644
--- a/exec/plugin-commands-script-runners/tsconfig.json
+++ b/exec/plugin-commands-script-runners/tsconfig.json
@@ -39,6 +39,9 @@
     {
       "path": "../../env/plugin-commands-env"
     },
+    {
+      "path": "../../env/system-node-version"
+    },
     {
       "path": "../../packages/core-loggers"
     },
diff --git a/pnpm-lock.yaml b/pnpm-lock.yaml
index 6d0b2800d1..817be5a8f6 100644
--- a/pnpm-lock.yaml
+++ b/pnpm-lock.yaml
@@ -2747,6 +2747,9 @@ importers:
         specifier: 'catalog:'
         version: 4.3.0
     devDependencies:
+      '@pnpm/env.system-node-version':
+        specifier: workspace:*
+        version: link:../../env/system-node-version
       '@pnpm/filter-workspace-packages':
         specifier: workspace:*
         version: link:../../workspace/filter-workspace-packages